Spravato®

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What Is SPRAVATO®?

SPRAVATO® is the only FDA-approved nasal spray for adults with treatment-resistant depression that can be taken with or without an oral antidepressant.

SPRAVATO® can help reduce depression symptoms when antidepressants haven’t worked well for you.

SPRAVATO® is the only FDA-approved nasal spray for treatment-resistant depression

SPRAVATO® is an NMDA receptor antagonist believed to work differently from traditional antidepressants by acting on glutamate.

While the exact role of glutamate in depression is unknown, it is a chemical messenger found in the brain that is thought to help regulate depression.

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